果蝇片段基因表达模式的时空登记。

Proceedings. International Conference on Intelligent Systems for Molecular Biology Pub Date : 1999-01-01

E M Myasnikova, D Kosman, J Reinitz, M G Samsonova

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摘要

应用图像配准技术，构建了果蝇分割基因在空间和时间上的完整图谱。该配准方法基于带柔性节的二次样条近似。开发了一种根据基因表达模式自动将胚胎归为时间类的分类器。

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Spatio-temporal registration of the expression patterns of Drosophila segmentation genes.

The application of image registration techniques resulted in the construction of an integrated atlas of Drosophila segmentation gene expression in both space and time. The registration method was based on a quadratic spline approximation with flexible knots. A classifier for automatic attribution of an embryo to one of the temporal classes according to its gene expression pattern was developed.)

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Proceedings. International Conference on Intelligent Systems for Molecular Biology

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