{"title":"当吸收常数和消去常数相等时，预测达到稳态所需的时间。","authors":"J Singer, L Vereczkey","doi":"10.1023/a:1020947130038","DOIUrl":null,"url":null,"abstract":"<p><p>A simple table is derived to facilitate the rapid estimation of the number of dose administrations needed to achieve a certain fraction of the steady-state plasma concentration in the case of one-compartment model with uniform multiple oral dosing and equal absorption and elimination constants.</p>","PeriodicalId":16765,"journal":{"name":"Journal of Pharmacokinetics and Biopharmaceutics","volume":"27 3","pages":"297-300"},"PeriodicalIF":0.0000,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1020947130038","citationCount":"1","resultStr":"{\"title\":\"Predicting the time needed to achieve steady state if absorption and elimination constants are equal.\",\"authors\":\"J Singer, L Vereczkey\",\"doi\":\"10.1023/a:1020947130038\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A simple table is derived to facilitate the rapid estimation of the number of dose administrations needed to achieve a certain fraction of the steady-state plasma concentration in the case of one-compartment model with uniform multiple oral dosing and equal absorption and elimination constants.</p>\",\"PeriodicalId\":16765,\"journal\":{\"name\":\"Journal of Pharmacokinetics and Biopharmaceutics\",\"volume\":\"27 3\",\"pages\":\"297-300\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1999-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1023/a:1020947130038\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pharmacokinetics and Biopharmaceutics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1023/a:1020947130038\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pharmacokinetics and Biopharmaceutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1023/a:1020947130038","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Predicting the time needed to achieve steady state if absorption and elimination constants are equal.
A simple table is derived to facilitate the rapid estimation of the number of dose administrations needed to achieve a certain fraction of the steady-state plasma concentration in the case of one-compartment model with uniform multiple oral dosing and equal absorption and elimination constants.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
