用PCR方法测定纤维蛋白原Banks半岛突变(gamma280Tyr- >Cys)的患病率。

Haemostasis Pub Date : 1999-01-01 DOI:10.1159/000022506

K Zimmermann, P L Turecek, H P Schwarz

{"title":"用PCR方法测定纤维蛋白原Banks半岛突变(gamma280Tyr- >Cys)的患病率。","authors":"K Zimmermann, P L Turecek, H P Schwarz","doi":"10.1159/000022506","DOIUrl":null,"url":null,"abstract":"A mutation of Tyr-->Cys at position 280 of the gamma chain of fibrinogen was recently determined to be the cause for fibrinogen Banks peninsula. A novel polymerase chain reaction/restriction digestion assay for this mutation was developed and used for the screening of 300 apparently healthy European blood donors. None of these subjects carried the mutation.","PeriodicalId":12910,"journal":{"name":"Haemostasis","volume":"29 4","pages":"225-8"},"PeriodicalIF":0.0000,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000022506","citationCount":"0","resultStr":"{\"title\":\"Determination of the prevalence of fibrinogen Banks peninsula mutation (gamma280Tyr-->Cys) by PCR.\",\"authors\":\"K Zimmermann, P L Turecek, H P Schwarz\",\"doi\":\"10.1159/000022506\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A mutation of Tyr-->Cys at position 280 of the gamma chain of fibrinogen was recently determined to be the cause for fibrinogen Banks peninsula. A novel polymerase chain reaction/restriction digestion assay for this mutation was developed and used for the screening of 300 apparently healthy European blood donors. None of these subjects carried the mutation.\",\"PeriodicalId\":12910,\"journal\":{\"name\":\"Haemostasis\",\"volume\":\"29 4\",\"pages\":\"225-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1999-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1159/000022506\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Haemostasis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000022506\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Haemostasis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000022506","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

纤维蛋白原γ链280位Tyr- >Cys突变最近被确定为纤维蛋白原Banks半岛的原因。开发了一种新的聚合酶链反应/限制性消化法，用于筛选300名明显健康的欧洲献血者。这些受试者都没有携带这种突变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Determination of the prevalence of fibrinogen Banks peninsula mutation (gamma280Tyr-->Cys) by PCR.

A mutation of Tyr-->Cys at position 280 of the gamma chain of fibrinogen was recently determined to be the cause for fibrinogen Banks peninsula. A novel polymerase chain reaction/restriction digestion assay for this mutation was developed and used for the screening of 300 apparently healthy European blood donors. None of these subjects carried the mutation.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Haemostasis

自引率

0.00%

发文量