钙在程序性细胞死亡中的重要作用综述

Cytobios Pub Date : 1999-01-01

P D Gupta, K Pushkala

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引用次数: 0

摘要

钙在细胞终末分化和凋亡等生理死亡过程中起重要作用。当细胞内钙池受到干扰时，就会发生细胞损伤，进而可能导致细胞死亡。钙依赖酶中的钙，如谷氨酰胺转胺酶、各种蛋白酶、磷酸化酶和激酶，参与细胞死亡的过程。这些酶参与细胞死亡的例子，以及钙水平在这些酶的调节中的作用，被描述和讨论。

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Importance of the role of calcium in programmed cell death: a review.

Calcium plays an important role in physiological cell death processes such as terminal differentiation and apoptosis. Cell injury occurs when the intracellular calcium pool is disturbed, which in turn may lead to cell death. Calcium in calcium-dependent enzymes, transglutaminases, various proteases, phosphorylases and kinase, is involved in the process of cell death. Examples of such enzymes involved in cell death, and the role of calcium levels in regulation of these enzymes, are described and discussed.

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Cytobios

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