短管内食道与抗反流手术:26例患者的研究

IF 0.6 4区 医学 Q4 SURGERY
J. Baulieux , J.Y. Mabrut , C. Ducerf , M. Adham , E. De La Roche , N. Berthoux , O. Bourdeix , J.L. Gaudin , J.C. Souquet
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引用次数: 9

摘要

研究目的本研究的目的是报告26例巴雷特食管患者接受抗反流手术治疗的回顾性研究结果。患者和方法:从1979年到1998年,21名男性和5名女性(平均年龄:53岁)接受了组织学证实为Barrett食管的抗反流手术。19例(73.1%)患者Barrett上皮平均长度为5.9 cm。舌Barrett上皮病变6例(23.1%),胃粘膜异位1例(3.8%)。所有患者术前食管活检均未发现高级别不典型增生或癌。其中开腹17例,腹腔镜9例。术前内镜局部氩凝治疗1例。结果临床平均随访78个月,内镜下平均随访59.3个月。未观察到巴雷特上皮长度增加。7例患者(27%)完全或部分消退(其中3例为舌部病变,1例术前行氩气治疗)。没有患者发生高度不典型增生或癌。结论抗反流手术后巴雷特食管有可能出现退行,但并不常见和不可预测。然而,术后应继续进行内镜和组织学检查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Endobrachyœsophage et chirurgie antireflux: étude d'une série de 26 patients

Study aim

The aim of this study was to report the results of a retrospective series of 26 patients with Barrett's esophagus treated by antireflux surgery.

Patients and methods

From 1979 to 1998, 21 men and five women (mean age: 53 years) with histologically proven Barrett's esophagus underwent an antireflux procedure. The mean length of Barrett's epithelium was 5.9 cm for 19 patients (73.1%).Six patients (23.1%) had tongue lesions of Barrett's epithelium, and one (3.8%) had ectopic gastric mucosa. None of the patients had a preoperative esophageal biopsy that revealed high-grade dysplasia or carcinoma. Laparotomy was performed in 17 cases and laparoscopy in nine cases. Preoperative endoscopic local treatment with argon coagulation was performed in one patient.

Results

Clinical mean follow-up was 78 months and endoscopic mean follow-up was 59.3 months. No increase in the length of the Barrett's epithelium was observed. Seven patients (27%) had complete or partial regression (among them three patients with tongue lesions and one patient preoperatively treated by argon). No patients developed high-grade dysplasia or carcinoma.

Conclusion

Regression of Barrett's esophagus is possible but not frequent and unpredictable after antireflux procedure. However, endoscopic and histological surveillance should be continued postoperatively.

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CiteScore
1.30
自引率
22.20%
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