[正常晶状体和白内障患者血液生化参数]。

I P Metelitsyna
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引用次数: 0

摘要

测定了健康人群(120人)和老年白内障患者(437人)血浆中Na+、K+ atp酶、γ -谷氨酰转肽酶、铜蓝蛋白活性、水溶性抗氧化剂总抗氧化活性、维生素C和E含量、游离氨基氮含量及红细胞抗氧化物能力。我们已经证明,与白内障发生有关的变化与年龄相关的变化是不相等的。Na+、K(+)- atp酶、γ -谷氨酰转肽酶活性和维生素E水平的降低在晶状体老化过程中表达较低,在晶状体混浊过程中表达较低。在白内障发生过程中氧化酶活性的增加不明显,然后是年龄依赖性的氧化酶抑制。水溶性抗氧化剂的总抗氧化活性表现出相反的趋势(白内障患者的活性降低更明显,而相应年龄的透明晶状体患者的这些参数的代偿性激活更明显)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Biochemical blood parameters in people with a normal crystalline lens and in cataracts].

The activity of Na+,K+ATPase, gamma-glutamyltranspeptidase, ceruloplasmin, total antioxidative activity of water-soluble antioxidants, the contents of vitamins C and E, free amino-nitrogen and peroxide resistance of erythrocytes were determined at the blood's plasma of healthy persons (120 persons) and suffered from aged cataract (437 persons) of three aged groups (up to 40 years, 40-60 years and elder then 60 years). We have shown, that changes, which has been connected with cataractogenesis and age dependent changes are not equal. The lowering of activity of Na+,K(+)-ATPase, gamma-glutamyltranspeptidase and level of vitamin E was expressed less during the ageing, then during the development of lenses opacification. The increase of activity of oxidase during the cataractogenesis is less significant, then age depended inhibition of this enzyme. The opposite tendency (the lowering of activity at the patients with cataract is more expressed, then compensatory activations of these parameters at the persons of the corresponding age with transparent lenses) was revealed for total antioxidative activity of water-soluble antioxidants.

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