{"title":"抗炎支架涂层:地塞米松及相关化合物。","authors":"S H Park, A M Lincoff","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The dexamethasone-eluting stent was a well-tolerated and effective means of providing sustained site-specific drug delivery to the porcine coronary artery wall for 28 days, although longer-term biocompatibility of the polymer coating was not assessed. Dexamethasone did not reduce the neointimal hyperplastic response to injury, despite sustained tissue levels of drug.</p>","PeriodicalId":79534,"journal":{"name":"Seminars in interventional cardiology : SIIC","volume":"3 3-4","pages":"191-5"},"PeriodicalIF":0.0000,"publicationDate":"1998-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Anti-inflammatory stent coatings: dexamethasone and related compounds.\",\"authors\":\"S H Park, A M Lincoff\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The dexamethasone-eluting stent was a well-tolerated and effective means of providing sustained site-specific drug delivery to the porcine coronary artery wall for 28 days, although longer-term biocompatibility of the polymer coating was not assessed. Dexamethasone did not reduce the neointimal hyperplastic response to injury, despite sustained tissue levels of drug.</p>\",\"PeriodicalId\":79534,\"journal\":{\"name\":\"Seminars in interventional cardiology : SIIC\",\"volume\":\"3 3-4\",\"pages\":\"191-5\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1998-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Seminars in interventional cardiology : SIIC\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminars in interventional cardiology : SIIC","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Anti-inflammatory stent coatings: dexamethasone and related compounds.
The dexamethasone-eluting stent was a well-tolerated and effective means of providing sustained site-specific drug delivery to the porcine coronary artery wall for 28 days, although longer-term biocompatibility of the polymer coating was not assessed. Dexamethasone did not reduce the neointimal hyperplastic response to injury, despite sustained tissue levels of drug.
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