人体测量值的遗传性估计。

S Chatterjee, N Das, P Chatterjee
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引用次数: 30

摘要

在54对双胞胎中,研究了遗传和环境因素对人体测量变异性的相对贡献。对30对同卵双胞胎(MZ)和24对异卵双胞胎(DZ)进行了研究,以估计遗传、环境和遗传因素对体重、站立高度、坐高、膝盖高度、臂幅、胸围和胆道直径等人体测量指标的影响。双性双胞胎组中,MZ组各指标的对内方差均显著小于DZ组(p < 0.05 ~ 0.01)。在MZ和DZ双胞胎中,这些测量值的对内相关性更高(p < 0.01)。MZ的相关值明显高于DZ。此外,所有测量值均为高遗传分量,遗传率估计在40% ~ 91%之间。将MZ和DZ双生子按年龄和性别划分为不同的亚群后,个体间变异发生了一定程度的改变。这些数据表明,遗传因素对人体测量的影响大于环境因素,此外,年龄和性别可能在一定程度上与遗传对人体测量的影响有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The estimation of the heritability of anthropometric measurements.

The relative contributions of genetic and environmental components in the variability of anthropometric measurements were studied in 54 twin pairs. Thirty pairs of monozygotic (MZ) and 24 pairs of dizygotic (DZ) twins were investigated to estimate the role of genetic, environmental and hereditary factors determining anthropometric measurements comprising body weight, standing height, sitting height, knee height, arm span, chest circumference and biiliac diameter. Within-pair variance for all the measurements were significantly smaller (p < 0.05-0.01) in MZ twins than in DZ twins of both-sex twin group. Within-pair correlations for those measurements were higher (p < 0.01) in both MZ and DZ twins. Correlation values were, apparently, higher more in MZ than in DZ twins. Besides, all the measurements are highly heritable components and heritability estimates ranged 40%-91%. When both MZ and DZ twin pairs of both-sex population were classified, based on age and sex, into different sub-groups interindividual variabilities were altered to a certain degrees. These data state that anthropometric measurements are influenced by genetic factors than environmental factors and besides, age and sex are possibly associated, to some extent, with the genetic influence upon anthropometric measurements.

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