[水溶性亚油酸-羟肟酸对脂蛋白修饰对动脉粥样硬化发展生化标志物的影响]。

Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-07-01

H M Chobot'ko

{"title":"[水溶性亚油酸-羟肟酸对脂蛋白修饰对动脉粥样硬化发展生化标志物的影响]。","authors":"H M Chobot'ko","doi":"","DOIUrl":null,"url":null,"abstract":"Effects of water-soluble form of linoleic-hydroxamic acid, inhibitor of lipoxygenase, on process of atherogenesis (alimentary model) were studied at rabbits. It was shown that inhibition of activity of lipoxygenase during process of development of atherosclerosis led to considerable decrease of area of lipoid plaques and lipoidosis, decreased content of cholesterol in blood and improved free-radical modification of lipoproteins of blood.","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 4","pages":"64-8"},"PeriodicalIF":0.0000,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Effects of modifications of lipoproteins by water soluble forms of lineoleic-hydroxamic acid on biochemical markers of development of atherosclerosis].\",\"authors\":\"H M Chobot'ko\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Effects of water-soluble form of linoleic-hydroxamic acid, inhibitor of lipoxygenase, on process of atherogenesis (alimentary model) were studied at rabbits. It was shown that inhibition of activity of lipoxygenase during process of development of atherosclerosis led to considerable decrease of area of lipoid plaques and lipoidosis, decreased content of cholesterol in blood and improved free-radical modification of lipoproteins of blood.\",\"PeriodicalId\":76775,\"journal\":{\"name\":\"Ukrainskii biokhimicheskii zhurnal (1978)\",\"volume\":\"70 4\",\"pages\":\"64-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1998-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ukrainskii biokhimicheskii zhurnal (1978)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ukrainskii biokhimicheskii zhurnal (1978)","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

研究了脂氧合酶抑制剂亚油酸-羟肟酸的水溶性形式对家兔动脉粥样硬化(消化道模型)的影响。结果表明，在动脉粥样硬化发展过程中，抑制脂氧合酶活性可显著减少脂质斑块和脂质沉积面积，降低血液中胆固醇含量，改善血液中自由基对脂蛋白的修饰。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

[Effects of modifications of lipoproteins by water soluble forms of lineoleic-hydroxamic acid on biochemical markers of development of atherosclerosis].

Effects of water-soluble form of linoleic-hydroxamic acid, inhibitor of lipoxygenase, on process of atherogenesis (alimentary model) were studied at rabbits. It was shown that inhibition of activity of lipoxygenase during process of development of atherosclerosis led to considerable decrease of area of lipoid plaques and lipoidosis, decreased content of cholesterol in blood and improved free-radical modification of lipoproteins of blood.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Ukrainskii biokhimicheskii zhurnal (1978)

自引率

0.00%

发文量