1989 ~ 1995年台湾两所教学医院分离的肺炎链球菌体外抗菌药物敏感性分析。

J Y Su, S C Chang, K T Luh, W C Hsieh
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引用次数: 0

摘要

对1989年10月~ 1995年5月在台大医院和台北市阳明医院采集的46株肺炎球菌进行了药敏试验。其中,青霉素G耐药率为21.7%;青霉素g耐药菌株对其他β -内酰胺类抗菌药物的耐药频率高于青霉素敏感菌株。所有分离株青霉素G的最低杀菌浓度(MBCs)均等于或比最低抑菌浓度(mic)高1倍。在用奥西林筛选的肺炎链球菌分离株中,有3株青霉素耐药假阳性。另一方面,对青霉素G的耐药往往独立于对红霉素的耐药。万古霉素是最具活性的药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
In Vitro antimicrobial susceptibilities of Streptococcus pneumoniae isolated from two teaching hospitals in Taiwan, 1989-1995.

The susceptibility of 46 pneumococcal isolates collected during October 1989 to May 1995 from National Taiwan University Hospital and Taipei Municipal Yang Ming Hospital was studied. Among these isolates, the resistant rate of penicillin G was 21.7%; the penicillin G-resistant strains were more frequently resistant than the penicillin-sensitive strains to other beta-lactam antimicrobial drugs. The minimum bactericidal concentrations (MBCs) of penicillin G for all isolates were equal to, or one dilution higher than, minimum inhibitory concentrations (MICs). Three strains were false positive for penicillin resistance among isolates of Streptococcus pneumoniae screened with oxacillin. On the other hand, resistance to penicillin G was often independent of resistance to erythromycin. Vancomycin was the most active agent tested.

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