{"title":"血小板活化因子在中枢神经系统功能和脑损伤中的作用","authors":"Giora Z. Feuerstein","doi":"10.1016/0929-7855(96)00516-0","DOIUrl":null,"url":null,"abstract":"<div><p>In the past 10 years evidence has been accumulating on the synthesis, distribution, regulation and function of platelet-activating factor (PAF) and related phospholipids in the brain. Clearly, much needs to be done to establish specific biological functions for PAF in the brain and in particular its role in disease processes. The cellular elements responsible for PAF synthesis and release in vivo is not yet clear nor has it been established whether PAF has a role in chronic pathological conditions. Hopefully, this ‘decade of the brain’ will lead us to better insights on these issues.</p></div>","PeriodicalId":79347,"journal":{"name":"Journal of lipid mediators and cell signalling","volume":"14 1","pages":"Pages 109-114"},"PeriodicalIF":0.0000,"publicationDate":"1996-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0929-7855(96)00516-0","citationCount":"13","resultStr":"{\"title\":\"Platelet-activating factor: A case for its role in CNS function and brain injury\",\"authors\":\"Giora Z. Feuerstein\",\"doi\":\"10.1016/0929-7855(96)00516-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In the past 10 years evidence has been accumulating on the synthesis, distribution, regulation and function of platelet-activating factor (PAF) and related phospholipids in the brain. Clearly, much needs to be done to establish specific biological functions for PAF in the brain and in particular its role in disease processes. The cellular elements responsible for PAF synthesis and release in vivo is not yet clear nor has it been established whether PAF has a role in chronic pathological conditions. Hopefully, this ‘decade of the brain’ will lead us to better insights on these issues.</p></div>\",\"PeriodicalId\":79347,\"journal\":{\"name\":\"Journal of lipid mediators and cell signalling\",\"volume\":\"14 1\",\"pages\":\"Pages 109-114\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1996-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0929-7855(96)00516-0\",\"citationCount\":\"13\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of lipid mediators and cell signalling\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0929785596005160\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of lipid mediators and cell signalling","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0929785596005160","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Platelet-activating factor: A case for its role in CNS function and brain injury
In the past 10 years evidence has been accumulating on the synthesis, distribution, regulation and function of platelet-activating factor (PAF) and related phospholipids in the brain. Clearly, much needs to be done to establish specific biological functions for PAF in the brain and in particular its role in disease processes. The cellular elements responsible for PAF synthesis and release in vivo is not yet clear nor has it been established whether PAF has a role in chronic pathological conditions. Hopefully, this ‘decade of the brain’ will lead us to better insights on these issues.
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