良性、非典型和恶性脑膜瘤的增殖细胞核抗原(PCNA)和核仁组织区(NORs)。

M C Lee, M W Kang, B S Yang, C S Park, S W Juhng, S Jung, J H Kim, S H Kim, S S Kang, J H Lee
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引用次数: 0

摘要

应用免疫组化和银染色技术研究了99例脑膜瘤中增殖细胞核抗原(PCNA)的表达和核核组织区(NORs)的数量及其与组织病理学分级、复发及其复发预测价值的关系。结果显示PCNA或AgNORs与脑膜瘤的组织病理学分级有显著相关性。非典型脑膜瘤中PCNA的高表达与复发率增高相关;然而,脑膜瘤中PCNA的表达和AgNORs的数量并不是预测肿瘤复发的可靠标准。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Proliferating cell nuclear antigen (PCNA) and nucleolar organizer regions (NORs) in benign, atypical and malignant meningiomas.

Expression of proliferating cell nuclear antigen (PCNA) and numbers of nucleolar organizer regions (NORs) were studied by immunohistochemistry and the silver staining technique in 99 meningiomas and related to histopathologic grading, recurrence and their predictive value for recurrence. The results indicated that there was a significant correlation between PCNA or AgNORs and histopathologic grading of meningiomas. Slightly higher expression of PCNA in atypical meningiomas was correlated with the increased recurrence rate; however, expression of PCNA and numbers of AgNORs in meningiomas are not reliable criteria to predict tumor recurrence.

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