HLA-DQA1多态性在西班牙巴斯克地区人群中的分布

B Esparza, C Pestoni, M D Martin, F Merino, A Carracedo
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引用次数: 0

摘要

在巴斯克地区人群中,采用PCR方法和ASO探针点印迹法测定HLA-DQA1位点的等位基因和基因型频率。结果表明与Hardy-Weinberg平衡没有偏差。三个巴斯克省之间没有发现差异,但基因频率与其他一些西班牙和世界人群的基因频率明显不同。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Distribution of the HLA-DQA1 polymorphism in the population of the Basque Country (Spain).

Allele and genotype frequencies at the HLA-DQA1 locus were determined in Basque Country populations using PCR methodology and a dot-blot assay with ASO probes. The results showed no deviation from the Hardy-Weinberg equilibrium. No differences were found between the three Basque Provinces, but gene frequencies were significantly different from those of some other Spanish and world populations.

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