W W Lorenz, M J Cormier, D J O'Kane, D Hua, A A Escher, A A Szalay
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Expression of the Renilla reniformis luciferase gene in mammalian cells.
A cDNA encoding the Renilla reniformis luciferase was expressed in similan and murine cells in a transient and stable manner, respectively. Light emission catalyzed by luciferase was detected from transfected cells both in vitro and in vivo. This work establishes the Renilla luciferase gene as a new efficient marker of gene expression in mammalian cells.
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