淋巴肉瘤中的血红蛋白氧转运活性。

IF 0.2 4区医学 Q4 HEMATOLOGY

Gematologiya I Transfuziologiya Pub Date : 1995-11-01

I V Karpova, M G Dmitrieva, A V Pivnik, E E Zybunova, I N Lutsenko

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引用次数: 0

摘要

为了评估Hb在淋巴样肉瘤中的氧转运功能，我们对15例16-63岁的患者进行了Hb氧容量、胎儿Hb和创造素浓度、碱性配体H+、CO2、2,3-二磷酸甘油(2,3- dpg)的检测。绘制了氧-血红蛋白解离曲线。患者血液中HbF含量升高，而红细胞中产生素含量升高。这强调了溶血在淋巴肉瘤贫血发生中的作用。70%的考生体内Hb对氧的亲和力保持正常，30%的考生体内Hb对氧的亲和力超标。这种疾病中导致Hb对氧亲和力低的代偿机制失效。因此淋巴肉瘤合并贫血患者需要早期补血。

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本刊更多论文

[Hemoglobin oxygen-transport activity in lymphosarcomas].

To evaluate oxygen transport function of Hb in lymphoid sarcomas, 15 patients aged 16-63 were examined for Hb oxygen capacity, concentrations of fetal Hb and creatinin, basic ligands H+, CO2, 2,3-diphosphoglycerate (2,3-DPG). Oxy-Hb dissociation curves were plotted. The patients' blood contained HbF in elevated quantities, whereas red cells had high creatinin. This emphasizes the role of hemolysis in genesis of anemia in lymphosarcomas. 70% of the examinees retained normal Hb affinity to oxygen in vivo, in 30% this affinity exceeded the standard. Compensatory mechanism responsible for low Hb affinity to oxygen in this disease fails. Therefore lymphosarcoma patients with anemia need early replacement hemotransfusions.

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来源期刊

Gematologiya I Transfuziologiya 医学-血液学

CiteScore

0.80

自引率

66.70%

发文量

审稿时长

>12 weeks

期刊介绍： The journal publishes original theoretical and clinical studies, lectures, reviews, and practical notes concerning various problems of hematology and clinical and industrial transfusion. The journal provides information on the etiology, pathogenesis, diagnosis and treatment of blood disorders as well as on related non-hematological conditions (internal diseases, poisoning, exposure to ionizing radiation etc.).