[可逆性食管功能障碍作为左旋多巴的副作用]。

Bildgebung = Imaging Pub Date : 1996-03-01
H Kellner, U Liegl, M Frank, W G Zoller
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引用次数: 0

摘要

我们报告一例94岁男性患者,有10年帕金森病病史,因急性食道梗阻入院。食管梗阻对内镜干预是难治的。然而,停止原有的左旋多巴药物导致其在数小时内解决。虽然吞咽困难常见于帕金森病患者,但在本病例中观察到的连续停药和梗阻消退表明左旋多巴的副作用尚未被报道。这种潜在的副作用应包括在帕金森病吞咽困难的鉴别诊断中,特别是老年患者,他们可能表现出左旋多巴的肠道吸收率增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Reversible esophageal dysfunction as a side effect of levodopa].

We are reporting the case of a 94-year-old male patient with a 10-year history of Parkinson's disease, who was admitted to our hospital with acute obstruction of esophageal passage. Esophageal obstruction was refractory to endoscopic intervention. However, discontinuation of the pre-existing levodopa medication led to its resolution within hours. While dysphagia is commonly encountered in patients with Parkinson's disease, the observed succession of drug discontinuation and resolution of obstruction in this case suggests an as yet rarely described side effect of levodopa. This potential side effect should be included in the differential diagnosis of dysphagia in Parkinson's disease, especially in the case of older patients, who may exhibit an increased rate of intestinal absorption of levodopa.

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