HIV感染的免疫发病机制:一种特异性的抗HIV耐受性作为控制疾病进展的机制。

I G Sidorovitch, G A Ignatieva
{"title":"HIV感染的免疫发病机制:一种特异性的抗HIV耐受性作为控制疾病进展的机制。","authors":"I G Sidorovitch,&nbsp;G A Ignatieva","doi":"10.2500/108854195778666829","DOIUrl":null,"url":null,"abstract":"<p><p>The pathogenesis of HIV has been evaluated by many investigators, yet the precise reasons for certain patients developing lethal infection while others appear to live for long periods tolerating the HIV virus remain to be determined. The immune response to HIV may be critical in the development of the fatal infected stated, while tolerance of the HIV virus may allow longer-term survival despite infection. The mechanisms for failure of immune protection from HIV and the subsequent development of immunodeficiency are likely related to the very nature of the immune response to the initial HIV infection.</p>","PeriodicalId":7423,"journal":{"name":"Allergy proceedings : the official journal of regional and state allergy societies","volume":"16 4","pages":"203-7"},"PeriodicalIF":0.0000,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2500/108854195778666829","citationCount":"1","resultStr":"{\"title\":\"Immunopathogenesis of HIV infection: a specific anti-HIV tolerance as a mechanism of control of disease progression.\",\"authors\":\"I G Sidorovitch,&nbsp;G A Ignatieva\",\"doi\":\"10.2500/108854195778666829\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The pathogenesis of HIV has been evaluated by many investigators, yet the precise reasons for certain patients developing lethal infection while others appear to live for long periods tolerating the HIV virus remain to be determined. The immune response to HIV may be critical in the development of the fatal infected stated, while tolerance of the HIV virus may allow longer-term survival despite infection. The mechanisms for failure of immune protection from HIV and the subsequent development of immunodeficiency are likely related to the very nature of the immune response to the initial HIV infection.</p>\",\"PeriodicalId\":7423,\"journal\":{\"name\":\"Allergy proceedings : the official journal of regional and state allergy societies\",\"volume\":\"16 4\",\"pages\":\"203-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1995-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.2500/108854195778666829\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Allergy proceedings : the official journal of regional and state allergy societies\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2500/108854195778666829\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Allergy proceedings : the official journal of regional and state allergy societies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2500/108854195778666829","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

许多研究人员已经对HIV的发病机制进行了评估,然而,某些患者发生致命感染,而另一些患者似乎长期耐受HIV病毒的确切原因仍有待确定。对艾滋病毒的免疫反应可能对致命感染的发展至关重要,而艾滋病毒的耐受性可能使感染后的存活时间更长。对HIV的免疫保护失效和随后的免疫缺陷发展的机制可能与对初始HIV感染的免疫反应的本质有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Immunopathogenesis of HIV infection: a specific anti-HIV tolerance as a mechanism of control of disease progression.

The pathogenesis of HIV has been evaluated by many investigators, yet the precise reasons for certain patients developing lethal infection while others appear to live for long periods tolerating the HIV virus remain to be determined. The immune response to HIV may be critical in the development of the fatal infected stated, while tolerance of the HIV virus may allow longer-term survival despite infection. The mechanisms for failure of immune protection from HIV and the subsequent development of immunodeficiency are likely related to the very nature of the immune response to the initial HIV infection.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信