血小板致密颗粒的数量随年龄、精神分裂症和痴呆而变化。

Dementia (Basel, Switzerland) Pub Date : 1995-11-01 DOI:10.1159/000106966

A Kessler, M Shinitzky, B Kessler

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引用次数: 7

摘要

在本研究中，我们观察到每个血小板的致密颗粒数量随着年龄的增长而增加，在大约40岁以上达到最大水平。新生儿血小板显然每个血小板只含有少量致密颗粒。与年龄匹配的健康对照相比，精神分裂症患者血小板致密颗粒的数量和血小板细胞大小增加。相反，与健康人相比，阿尔茨海默型痴呆症患者血小板致密颗粒的数量有减少的趋势。

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Number of platelet dense granules varies with age, schizophrenia and dementia.

In the present study we observed that the number of dense granules per platelet increases with age, attaining a maximum level above the age of about 40 years. Platelets of newborns apparently contain only a small number of dense granules per platelet. The numbers of platelet dense granules and platelet cell size in schizophrenic patients increase compared to age-matched healthy controls. In contrast, in Alzheimer-type dementia the number of platelet dense granules tends to decrease compared to healthy persons.

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来源期刊

Dementia (Basel, Switzerland)

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