【原发性胃肠道淋巴瘤的分期程序】。

L Tedeschi
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引用次数: 0

摘要

非霍奇金淋巴瘤(NHL)通常是一种全身性疾病,几乎可以累及任何器官或组织。尽管如此,原发性结外疾病在非hl中也很常见,一些定位是由于预后较差(脑,睾丸)而完成的,其他,特别是原发性胃肠道受累,在很高比例的病例中可以通过手术,化疗和放疗治愈。胃肠道定位的症状无特征性:腹痛频繁,其他胃肠道疾病也可出现其他症状。内窥镜、放射学和外科是最重要的诊断程序。第一种是提供有关疾病的重要信息,并允许术前诊断。第二种是用于检测淋巴结延伸(CT扫描和MRI成像)和内在胃或肠道受累(胃肠道对比放射学)。第三个是重要的诊断和治疗时刻。由于其潜在的发病率和死亡率,一些作者最近不同意这种侵入性手术。确定NHL患者的疾病程度非常重要,具有多种目的:关于潜在并发症的紧迫性的信息,预后指征和治疗计划。最常用的分期系统是Ann Arbor方案,最初是为HG疾病设计的。该方案尤其不适用于原发性胃肠道NHL。其他方案,如Blackledge或Mushoff方案显示肿瘤负荷、淋巴结和结外受累之间的相关性更强。准确的诊断,精确的分期和正确的治疗带来了潜在的治愈能力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Procedures for staging primary gastrointestinal lymphoma].

The non-Hodgkin's lymphomas (NHL) are usually generalized diseases and can involve almost any organ or tissue. Nevertheless also primary extranodal disease is frequent in NHL and some localizations are accomplished by a worse prognosis (brain, testicle) other, in particular primary gastrointestinal involvement, can be cured in a high percentage of cases with surgery, chemotherapy and radiotherapy. The gastrointestinal localization's symptomatology is not characteristic: abdominal pain is frequent and other symptoms can be present in other gastrointestinal diseases. Endoscopy, radiology and surgery are the most important diagnostic procedures. The first gives important information about the disease and it permits pre-operative diagnosis. The second is useful to detect both nodal extension (CT scan and MRI imaging) and intrinsic stomach or bowel involvement (contrast radiology of the gastrointestinal tract). The third is an important diagnostic and therapeutic moment. Some Authors recently don't agree with this invasive procedures routinely because of its potential morbidity and mortality. The determination of the extent of disease in patients with NHL is very important and serves multiple purposes: information regarding the imminence of potential complications, indication of prognosis and treatment planning. The most used staging system is the Ann Arbor scheme, originally designed for HG disease. This scheme is inadequate in particular for primary gastrointestinal NHL. Others, like Blackledge or Mushoff schemes show more correlation between tumor burden, nodal and extranodal involvement. An exact diagnosis, precise staging and a correct treatment bring to a potential curability.

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