R M Srapionian, R O Karapetian, A A Galoian, T M Vinogradova, N A Sokolova
{"title":"[一种具有心脏活性的下丘脑神经激素对离体大鼠心脏的影响]。","authors":"R M Srapionian, R O Karapetian, A A Galoian, T M Vinogradova, N A Sokolova","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>On the isolated perfused by Langendorf at heart the cardioactive hypothalamic neurohormone NG3a (2 x 10(-5) g/ml) significantly decreased the coronary flow rate; the effect persisted during 5-10 min, after that the second phase appeared which was expressed by the increase of coronary flow rate. The maximum effect was 122% compared with control. The second phase appeared in 30-45 min after infusion of NG3a. NG3a did not influence the heart rate, but sometimes (7.3% cases) during the maximum increase of coronary flow the bradyarrhythmia was registered. It has been concluded that NG3a influences directly the coronary vessels.</p>","PeriodicalId":18920,"journal":{"name":"Nauchnye doklady vysshei shkoly. Biologicheskie nauki","volume":" 1","pages":"115-7"},"PeriodicalIF":0.0000,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The effects of a cardioactive hypothalamic neurohormone on the isolated rat heart].\",\"authors\":\"R M Srapionian, R O Karapetian, A A Galoian, T M Vinogradova, N A Sokolova\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>On the isolated perfused by Langendorf at heart the cardioactive hypothalamic neurohormone NG3a (2 x 10(-5) g/ml) significantly decreased the coronary flow rate; the effect persisted during 5-10 min, after that the second phase appeared which was expressed by the increase of coronary flow rate. The maximum effect was 122% compared with control. The second phase appeared in 30-45 min after infusion of NG3a. NG3a did not influence the heart rate, but sometimes (7.3% cases) during the maximum increase of coronary flow the bradyarrhythmia was registered. It has been concluded that NG3a influences directly the coronary vessels.</p>\",\"PeriodicalId\":18920,\"journal\":{\"name\":\"Nauchnye doklady vysshei shkoly. Biologicheskie nauki\",\"volume\":\" 1\",\"pages\":\"115-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nauchnye doklady vysshei shkoly. Biologicheskie nauki\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nauchnye doklady vysshei shkoly. Biologicheskie nauki","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[The effects of a cardioactive hypothalamic neurohormone on the isolated rat heart].
On the isolated perfused by Langendorf at heart the cardioactive hypothalamic neurohormone NG3a (2 x 10(-5) g/ml) significantly decreased the coronary flow rate; the effect persisted during 5-10 min, after that the second phase appeared which was expressed by the increase of coronary flow rate. The maximum effect was 122% compared with control. The second phase appeared in 30-45 min after infusion of NG3a. NG3a did not influence the heart rate, but sometimes (7.3% cases) during the maximum increase of coronary flow the bradyarrhythmia was registered. It has been concluded that NG3a influences directly the coronary vessels.
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