{"title":"[中子暴露前后视网膜结构元素的变化]。","authors":"S V Logvinov, N P Buĭmova","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Local fractionated exposure of a rabbit eye to fast neutrons of 3 Gy (1.5 x 2) and 7.5 Gy (1.5 x 5) induces early reactions of all structural elements of retina, among which dose-dependent degradation of photoreceptor membrane discs and damages to pigmentoepitheliocytes are of prime importance. Further pathomorphogenesis is connected with the surpassing degeneration of a radial glia with respect to destruction of interneuronal synapses and a minor part of neurons. The postirradiation (one and six months after 7.5 Gy irradiation) changes in the blood-retinal barrier are responsible for the disturbances in the glioneuronal complex.</p>","PeriodicalId":20808,"journal":{"name":"Radiobiologiia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Changes in the retinal structural elements in the early and late periods after neutron exposure].\",\"authors\":\"S V Logvinov, N P Buĭmova\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Local fractionated exposure of a rabbit eye to fast neutrons of 3 Gy (1.5 x 2) and 7.5 Gy (1.5 x 5) induces early reactions of all structural elements of retina, among which dose-dependent degradation of photoreceptor membrane discs and damages to pigmentoepitheliocytes are of prime importance. Further pathomorphogenesis is connected with the surpassing degeneration of a radial glia with respect to destruction of interneuronal synapses and a minor part of neurons. The postirradiation (one and six months after 7.5 Gy irradiation) changes in the blood-retinal barrier are responsible for the disturbances in the glioneuronal complex.</p>\",\"PeriodicalId\":20808,\"journal\":{\"name\":\"Radiobiologiia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Radiobiologiia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiobiologiia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
兔眼局部局部暴露于3gy (1.5 x 2)和7.5 Gy (1.5 x 5)的快中子可诱导视网膜所有结构元件的早期反应，其中光感受器膜盘的剂量依赖性降解和色素上皮细胞的损伤是最重要的。进一步的病理形态发生与放射状胶质细胞的过度变性有关，涉及神经元间突触和一小部分神经元的破坏。放射后(7.5 Gy照射后1个月和6个月)血液-视网膜屏障的变化是造成胶质神经元复合物紊乱的原因。
[Changes in the retinal structural elements in the early and late periods after neutron exposure].
Local fractionated exposure of a rabbit eye to fast neutrons of 3 Gy (1.5 x 2) and 7.5 Gy (1.5 x 5) induces early reactions of all structural elements of retina, among which dose-dependent degradation of photoreceptor membrane discs and damages to pigmentoepitheliocytes are of prime importance. Further pathomorphogenesis is connected with the surpassing degeneration of a radial glia with respect to destruction of interneuronal synapses and a minor part of neurons. The postirradiation (one and six months after 7.5 Gy irradiation) changes in the blood-retinal barrier are responsible for the disturbances in the glioneuronal complex.
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