[大戟叶和大戟叶提取物混合物对小鼠分级辐照的抗辐射作用]。

Radiobiologiia Pub Date : 1993-03-01
A A Narimanov
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引用次数: 0

摘要

在小鼠实验中,研究了单剂量樟子树和棕榈叶的提取物混合物对分次γ辐照(剂量为1和4 Gy,累积剂量为12 Gy)引起的辐射损伤的严重程度的有利影响。在第一次剂量为4gy之前注射该混合物(间隔2-7天给药3次),对暴露小鼠的存活率和平均预期寿命都有显著降低。在分级辐照条件下,随着累积辐照剂量效率的降低,提取物混合物的防护效果逐渐增强。结果表明,所使用的混合物可以保护动物免受胃肠道和造血系统的损伤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[The antiradiation effectiveness of a mixture of Archangelica officinalis and Ledum palustre extracts in the fractionated gamma irradiation of mice].

In experiments with mice a study was made of the favourable effect of a single dose of a mixture of extracts from Archangelica officinalis and Ledum palustre on the severity of radiation injury induced by fractionated gamma irradiation (doses of 1 and 4 Gy, cumulative dose of 12 Gy). Injection of the mixture prior to the first dose of 4 Gy (given 3 times at a 2-7 day interval) caused a significant decrease in the damaging effect with respect to both the survival rate and the average life expectancy of exposed mice. With fractionated irradiation, the protective effect of the extract mixture increased with decreasing efficiency of the cumulative radiation dose. The results obtained indicate that the mixture used protects the animals from the injury to both the gastrointestinal tract and the haemopoietic system.

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