菝葜提取物的抗疱疹作用。

Q4 Biochemistry, Genetics and Molecular Biology

Acta Microbiologica Bulgarica Pub Date : 1993-01-01

Z Dimitrova, B Dimov, N Manolova, S Pancheva, D Ilieva, S Shishkov

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引用次数: 0

摘要

研究了梅丽莎提取物(M1、M3、M3和M4)对1型单纯疱疹病毒(HSV-1)的毒力和抗病毒作用。在MTC中使用M4在3和6小时内观察到抗病毒效果。剩下的提取物在第12和24小时灭活病毒。M1、M2和M3对同一病毒体外或体内的抑制活性均无显著值。薄层色谱法证实了咖啡酸、迷迭香酸和阿魏酸的存在。讨论了它们在officinalis L.抗病毒活性中的作用。

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Antiherpes effect of Melissa officinalis L. extracts.

Studies were carried out on the virucidal and antiviral effects of Melissa officinalis L. extracts (M1, M3, M3 and M4) with respect to Herpes simplex virus type 1 (HSV-1). Virucidal effect was registered within 3 and 6 hours of treatment using M4 administered in MTC. The remaining extracts inactivate the virus at the 12th and 24th hour. No significant values of inhibiting activity of M1, M2, and M3 on the same virus in vitro or in vivo were demonstrated. The presence of caffeic, rosmarinic and ferulic acids was demonstrated by thin-layer chromatography. Their role in the antiviral activity of M. officinalis L. is discussed.

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来源期刊

Acta Microbiologica Bulgarica Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

0.40

自引率

0.00%

发文量