[低剂量和亚致死剂量电离辐射对不同品系小鼠生精上皮功能和显性致死突变产生的影响]。

Radiobiologiia Pub Date : 1993-05-01
V P Mamina, L D Sheĭko
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引用次数: 0

摘要

1.0 Gy剂量的BALB/c小鼠辐照后,具有小头的精子增加30%,“年轻”精子增加3倍。在0.1 ~ 1.0 Gy的辐射剂量下,BALB/c和CBA小鼠(在精原细胞活力、支持细胞数量和胚胎总死亡率方面存在差异)在精原细胞和干细胞阶段的着床前死亡显著增加。所获得的结果表明精子受精能力的降低,这可能是显性致死突变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[The effect of low and sublethal doses of ionizing radiation on the function of the spermatogenic epithelium and the yield of dominant lethal mutations in different strains of mice].

There was a 30% increase in spermatozoids with microheads and a 3-fold increase in "young" spermatozoids at later times after irradiation of BALB/c mice a dose of 1.0 Gy. With radiation doses of 0.1-1.0 Gy, BALB/c and CBA mice (which differ in viability of spermatogenous cells, the number of Sertoli cells and total embryonal death rate) exhibited a significant increase in the preimplantation death at the stage of spermatogonia and stem cells. The results obtained indicate reduction of the fertilizing capacity of sperm which is probably realized as dominant lethal mutations.

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