[血卟啉衍生物对小鼠术后造血功能恢复的影响]。

Radiobiologiia Pub Date : 1993-05-01

Iu B Deshevoĭ, B B Moroz, G I Bezin, V Iu Kovtun, G V Ponomarev, G V Kirillova

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引用次数: 0

摘要

在暴露于γ量子(6.0 Gy)的小鼠实验中，研究表明，在照射前15分钟和照射后15分钟，单次注射2,4-二(α -甲氧基乙基)重卟啉IX二钠盐(50和12 mg/kg)可促进所有骨髓造血室的放射后再生。该制剂在辐照后施用时产生更明显的刺激作用。

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[The effect of hematoporphyrin derivative on the postradiation recovery of hemopoiesis in mice].

In experiments with mice exposed to gamma quanta (6.0 Gy) it was shown that a single injection of disodium salt of 2,4-di(alpha-methoxyethyl)deuteroporphyrin IX (50 and 12 mg/kg) both 15 min before and 15 min after irradiation promoted postirradiation regeneration of all bone marrow haemopoiesis compartments. The agent produced a more pronounced stimulatory effect when administered after irradiation.

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Radiobiologiia

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