术中诊断嗜铬细胞瘤的麻醉处理—1例报告。

P S Tsai, K L Wong
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引用次数: 0

摘要

嗜铬细胞瘤是一种起源于肾上腺髓质(高达90%)或沿椎旁交感神经链的嗜铬组织的分泌儿茶酚胺的肿瘤。嗜铬细胞瘤的标志是阵发性高血压,伴有出汗、头痛、颤抖和心悸。高血压患者的出汗、心动过速和头痛三联征是嗜铬细胞瘤的高度提示。然而,其他症状如脸红、恶心、呕吐、性格改变和视觉障碍可能会对嗜铬细胞瘤的诊断产生怀疑。嗜铬细胞瘤导致的死亡通常是由于充血性心力衰竭、心肌梗死或脑出血。虽然只有不到0.1%的高血压患者患有嗜铬细胞瘤,但近50%的未被怀疑的嗜铬细胞瘤死亡发生在麻醉、手术或分娩期间。未经诊断的嗜铬细胞瘤患者有更高的手术风险,因为一些强制性的术前治疗可能被忽视了。在麻醉和手术过程中如何处理意料之外的高血压危象也是麻醉师面临的挑战。我们报告了一例意外的嗜铬细胞瘤,被外科医生误诊,并作为普通肾上腺肿瘤治疗,并计划手术治疗。当病人接受肿瘤切除时,对肿瘤的操作引起了血压的急剧升高。在回顾她的运动正常、视觉障碍、恶心和不安的病史后,她立即被当作嗜铬细胞瘤治疗。采用适当的控制措施,成功控制了患者异常高的波动血压,无并发症和不良反应。(摘要删节250字)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Anesthetic management of intraoperatively diagnosed pheochromocytoma--a case report].

Pheochromocytoma is a catecholamine secreting tumor originating from the adrenal medulla (up to 90%), or from the chromaffin tissue along the paravertebral sympathetic chain. The hallmark of pheochromocytoma is paroxysmal hypertension associated with diaphoresis, headache, tremulousness, and palpitations. The triad of diaphoresis, tachycardia, and headache in hypertensive patients is highly suggestive of pheochromocytoma. Other symptoms like flushing, nausea, vomiting, personality changes, and visual disturbances may however cast doubt on the diagnosis of pheochromocytoma. Death resulting from pheochromocytoma is usually due to congestive heart failure, myocardial infarction, or intracerebral hemorrhage. Although less than 0.1 percent of patients with hypertension have a pheochromocytoma, nearly 50 percent of the mortality with unsuspected pheochromocytoma occurred during anesthesia and surgery or parturition. Patients of unsuspected pheochromocytoma have higher risk for surgery, because some mandatory pre-op medical treatments might have been ignored. It is also a challenge to anesthesiologists to handle unsuspected hypertensive crisis during anesthesia and surgery. We presented such a case of unexpected Pheochromocytoma which was mis-diagnosed by the surgeon and was treated as an ordinary adrenal gland tumor and was scheduled for surgical operation. When the patient was undergoing excision of the tumor, manipulations of the tumor initiated an tremendous elevation of the blood pressure. Upon reviewing her history of normotension with visual disturbance, nausea and restlessness, she was immediate treated as with a pheochromocytoma. Appropriate managements were applied to control her abnormally high fluctuating blood pressure with success and with no complications or adverse effect.(ABSTRACT TRUNCATED AT 250 WORDS)

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