{"title":"心房利钠肽样免疫反应物质(ANP-LI)通过内脏神经刺激从肾上腺释放。","authors":"L Duntas, S R Bornstein, W A Scherbaum, J J Holst","doi":"10.1055/s-0029-1211260","DOIUrl":null,"url":null,"abstract":"<p><p>We investigated the release of atrial natriuretic peptide-like immunoreactive material (ANP-LI) after splanchnic nerve stimulation of isolated perfused adrenal glands. Electrical stimulation of the splanchnic nerves caused a statistically significant increase of ANP-LI (186 +/- 12 pg.min-1; p < 0.05) at 5 min. after stimulation. The integrated ANP-LI release after stimulation was amounted to 354 +/- 6.8% over basal. The regulation of ANP through the sympathoadrenal system may indicate an important role of ANP in adrenal steroidogenesis.</p>","PeriodicalId":12104,"journal":{"name":"Experimental and clinical endocrinology","volume":"101 6","pages":"371-3"},"PeriodicalIF":0.0000,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0029-1211260","citationCount":"6","resultStr":"{\"title\":\"Atrial natriuretic peptide-like immunoreactive material (ANP-LI) is released from the adrenal gland by splanchnic nerve stimulation.\",\"authors\":\"L Duntas, S R Bornstein, W A Scherbaum, J J Holst\",\"doi\":\"10.1055/s-0029-1211260\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We investigated the release of atrial natriuretic peptide-like immunoreactive material (ANP-LI) after splanchnic nerve stimulation of isolated perfused adrenal glands. Electrical stimulation of the splanchnic nerves caused a statistically significant increase of ANP-LI (186 +/- 12 pg.min-1; p < 0.05) at 5 min. after stimulation. The integrated ANP-LI release after stimulation was amounted to 354 +/- 6.8% over basal. The regulation of ANP through the sympathoadrenal system may indicate an important role of ANP in adrenal steroidogenesis.</p>\",\"PeriodicalId\":12104,\"journal\":{\"name\":\"Experimental and clinical endocrinology\",\"volume\":\"101 6\",\"pages\":\"371-3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1055/s-0029-1211260\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Experimental and clinical endocrinology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/s-0029-1211260\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experimental and clinical endocrinology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/s-0029-1211260","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Atrial natriuretic peptide-like immunoreactive material (ANP-LI) is released from the adrenal gland by splanchnic nerve stimulation.
We investigated the release of atrial natriuretic peptide-like immunoreactive material (ANP-LI) after splanchnic nerve stimulation of isolated perfused adrenal glands. Electrical stimulation of the splanchnic nerves caused a statistically significant increase of ANP-LI (186 +/- 12 pg.min-1; p < 0.05) at 5 min. after stimulation. The integrated ANP-LI release after stimulation was amounted to 354 +/- 6.8% over basal. The regulation of ANP through the sympathoadrenal system may indicate an important role of ANP in adrenal steroidogenesis.
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