{"title":"脊髓损伤男性对精子的自身免疫和精液质量。","authors":"A Siösteen, Y Steen, L Forssman, L Sullivan","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To determine the presence of anti-sperm antibodies in serum, and on spermatozoa, in men with spinal cord injury.</p><p><strong>Design: </strong>Thirty men whose injury occurred 1 to 18 years ago compared with 30 men with normal semen.</p><p><strong>Patients and interventions: </strong>Eighteen tetraplegic and 12 paraplegic patients were treated with vibrator or rectal electrostimulation, yielding a total of 25 ejaculates.</p><p><strong>Results: </strong>Semen analyses (WHO): volume low, with concentration > 100 million/mL in 80%; 8/30 exhibited sperm agglutinating antibodies, but with low titres.</p><p><strong>Conclusions: </strong>Low titres of serum antibodies and absence of attached IgA antibodies indicate autoimmunity is not the cause of low sperm motility and penetration capacity in these patients.</p>","PeriodicalId":13990,"journal":{"name":"International Journal of Fertility","volume":"38 2","pages":"117-22"},"PeriodicalIF":0.0000,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Auto-immunity to spermatozoa and quality of semen in men with spinal cord injury.\",\"authors\":\"A Siösteen, Y Steen, L Forssman, L Sullivan\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To determine the presence of anti-sperm antibodies in serum, and on spermatozoa, in men with spinal cord injury.</p><p><strong>Design: </strong>Thirty men whose injury occurred 1 to 18 years ago compared with 30 men with normal semen.</p><p><strong>Patients and interventions: </strong>Eighteen tetraplegic and 12 paraplegic patients were treated with vibrator or rectal electrostimulation, yielding a total of 25 ejaculates.</p><p><strong>Results: </strong>Semen analyses (WHO): volume low, with concentration > 100 million/mL in 80%; 8/30 exhibited sperm agglutinating antibodies, but with low titres.</p><p><strong>Conclusions: </strong>Low titres of serum antibodies and absence of attached IgA antibodies indicate autoimmunity is not the cause of low sperm motility and penetration capacity in these patients.</p>\",\"PeriodicalId\":13990,\"journal\":{\"name\":\"International Journal of Fertility\",\"volume\":\"38 2\",\"pages\":\"117-22\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Fertility\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Fertility","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Auto-immunity to spermatozoa and quality of semen in men with spinal cord injury.
Objective: To determine the presence of anti-sperm antibodies in serum, and on spermatozoa, in men with spinal cord injury.
Design: Thirty men whose injury occurred 1 to 18 years ago compared with 30 men with normal semen.
Patients and interventions: Eighteen tetraplegic and 12 paraplegic patients were treated with vibrator or rectal electrostimulation, yielding a total of 25 ejaculates.
Results: Semen analyses (WHO): volume low, with concentration > 100 million/mL in 80%; 8/30 exhibited sperm agglutinating antibodies, but with low titres.
Conclusions: Low titres of serum antibodies and absence of attached IgA antibodies indicate autoimmunity is not the cause of low sperm motility and penetration capacity in these patients.
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