[成人Schoenlein-Henoch综合征的现状]。

C de Pree, J A Schifferli, I Masouye, P Bernard
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引用次数: 0

摘要

Schoenlein-Henoch紫癜临床表现为可触及性紫癜,主要发生在腿部,不同程度累及胃肠道、关节和肾脏。肾脏受累在成人中往往比在儿童中更严重,它往往决定了疾病的结局。Schoenlein-Henoch紫癜也以iga血管炎为特征,可能由几种非特异性抗原因子引发。其发病机制尚不清楚,但已证实IgA免疫系统功能障碍。我们讨论解剖-临床,治疗和致病方面的这种综合征根据今天的知识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Schoenlein-Henoch syndrome in adults--current aspects].

Schoenlein-Henoch purpura is characterized clinically by palpable purpura, mainly on the legs, with varying degrees of gastrointestinal, articular and renal involvement. Renal involvement is often more severe in the adult than in children and it often determines the outcome of the disease. Schoenlein-Henoch purpura is also characterized by an IgA-vasculitis, which may be triggered by several non-specific antigenic factors. Its pathogenesis is still unclear, but a dysfunction of the IgA immune system has been demonstrated. We discuss the anatomo-clinical, therapeutic and etiopathogenic aspects of this syndrome according to today's knowledge.

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