自体移植物微小残留病的检测

ImmunoMethods Pub Date : 1994-12-01 DOI:10.1006/immu.1994.1060

Moss Thomas J.

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引用次数: 0

摘要

越来越多的证据表明，自体造血细胞移植物中肿瘤细胞的存在可能增加移植后疾病复发的风险。因此，无论移植物来源如何，对微小残留疾病的敏感检测对于改善自体移植的结果至关重要。本文综述了目前可用的肿瘤检测方法的敏感性和特异性的比较评价。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Detection of Minimal Residual Disease in Autologous Grafts

There is increasing evidence that the presence of tumor cells within autologous hematopoietic cell grafts may increase the risk of relapse of disease post-transplant. The sensitive detection of minimal residual disease is therefore central to improving the outcome of autologous transplantation, irrespective of the source of the graft. This review presents a comparative evaluation of the sensitivity and specificity of the currently available methods for tumor detection.

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ImmunoMethods

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