Non-steroidal anti-inflammatory drugs in everyday practice.

Problems of theoretical and practical importance of non-steroidal anti-inflammatory drug therapies have been reviewed on the basis of data of references. Recent observations, which may explain the differences in the clinical effectiveness and toxicity of the different products, have been emphasized. Attention has been called to the great individual variations in the patients' responses and the development of unwanted effects. The risks of the use of non-steroidal anti-inflammatory drugs in elderly have been pointed out. The author stresses the importance of a proper drug selection and calls attention to the fact that the continuous use of a non-steroidal anti-inflammatory agents is not necessary in a great number of cases.