{"title":"大鼠红细胞膜唾液糖蛋白与人糖蛋白的免疫学关系。","authors":"A Herráez, A Díaz, J Luque, J C Díez","doi":"10.1016/0020-711x(93)90114-t","DOIUrl":null,"url":null,"abstract":"<p><p>1. Specific antibodies against a whole preparation of glycophorins from rat erythrocyte membrane and against its most prominent component (32 kDa) were prepared. 2. Both antisera and the respective affinity-purified antibodies recognize the 74, 32 and 25 kDa components of rat glycophorins; therefore, a close antigenic relationship between them can be inferred. 3. On the other hand, a cross-reaction with human glycophorin A (both MM- and NN-type) is observed for both antisera. 4. This suggests the existence of epitopes common to human and rat glycophorins.</p>","PeriodicalId":22539,"journal":{"name":"The International journal of biochemistry","volume":"25 7","pages":"1009-14"},"PeriodicalIF":0.0000,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0020-711x(93)90114-t","citationCount":"2","resultStr":"{\"title\":\"Immunological relationship among rat erythrocyte membrane sialoglycoproteins and with human glycophorins.\",\"authors\":\"A Herráez, A Díaz, J Luque, J C Díez\",\"doi\":\"10.1016/0020-711x(93)90114-t\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>1. Specific antibodies against a whole preparation of glycophorins from rat erythrocyte membrane and against its most prominent component (32 kDa) were prepared. 2. Both antisera and the respective affinity-purified antibodies recognize the 74, 32 and 25 kDa components of rat glycophorins; therefore, a close antigenic relationship between them can be inferred. 3. On the other hand, a cross-reaction with human glycophorin A (both MM- and NN-type) is observed for both antisera. 4. This suggests the existence of epitopes common to human and rat glycophorins.</p>\",\"PeriodicalId\":22539,\"journal\":{\"name\":\"The International journal of biochemistry\",\"volume\":\"25 7\",\"pages\":\"1009-14\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0020-711x(93)90114-t\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The International journal of biochemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/0020-711x(93)90114-t\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The International journal of biochemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/0020-711x(93)90114-t","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Immunological relationship among rat erythrocyte membrane sialoglycoproteins and with human glycophorins.
1. Specific antibodies against a whole preparation of glycophorins from rat erythrocyte membrane and against its most prominent component (32 kDa) were prepared. 2. Both antisera and the respective affinity-purified antibodies recognize the 74, 32 and 25 kDa components of rat glycophorins; therefore, a close antigenic relationship between them can be inferred. 3. On the other hand, a cross-reaction with human glycophorin A (both MM- and NN-type) is observed for both antisera. 4. This suggests the existence of epitopes common to human and rat glycophorins.
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