[外科牙齿重建结合恶性肿瘤的照射]。

G M Henrich, K Grötz, T Diwo, W Wagner
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引用次数: 0

摘要

感染性放射性骨坏死(IORN)是头颈部肿瘤放疗过程中最严重的后遗症之一。为了防止这种情况的发生,在放射治疗前需要预防性拔牙,如果在放射治疗后必须拔牙,则需要采取具体措施(骨膜外整形覆盖、围手术期抗生素治疗)。从1980年至1993年,有812名必须接受放射治疗的病人接受了预防性拔牙方案。在这些病例中,只有0.5%的人后来发展为受感染的放射性骨坏死。167例患者放射治疗后,围手术期抗生素治疗和精心软组织覆盖龈外膜准备。尽管有25%的局部开裂,但没有观察到骨的立即感染。同时治疗感染性放射性骨坏死53例,其中牙源性骨坏死占43%。多数可见于下磨牙区。结果表明,放疗前预防性拔牙具有较高的价值,同时在放疗后,特别是在后下牙槽区,有龈周盖的谨慎拔牙是有益的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Surgical tooth reconstruction in conjunction with irradiation of malignant tumors].

An infected osteoradionecrosis (IORN) is one of the most problematic sequelae of radiation in the course of cancer treatment in the head and neck. To prevent this, prophylactic dental extractions have been demanded before radiation, as well as specific measures (epiperiostalplastic cover, perioperative antibiotic treatment) if a tooth has to be extracted after the radiation treatment has been carried out. From 1980 until 1993, 812 Patients who had to be irradiated underwent a prophylactic dental extraction programme. Only in 0.5% of these cases an infected osteoradionecrosis developed later on. 167 patients were treated after the radiation had been applied, using perioperative antibiotic treatment and meticulous soft tissue cover following epiperiostal preparation of the gingiva. In spite of 25% of localised dehiscences no immediate infection of the bone was observed. At the same time 53 infected osteoradionecrosis were treated, 43% of which were of dental origin. Most of these were seen in the lower molar area. The results show the high value of prophylactic dental extractions before radiation as well as the benefit of careful extractions with epiperiostal gingival cover, after the radiation treatment, especially in the area of the posterior lower alveolus.

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