白细胞己糖激酶活性与老年痴呆症的关系。

Dementia (Basel, Switzerland) Pub Date : 1995-07-01 DOI:10.1159/000106947

P G Antuono, J Ravanelli-Meyer, K Nicholson, A S Bloom

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引用次数: 4

摘要

我们确定了临床变量对阿尔茨海默病(AD)患者和对照组白细胞己糖激酶(HK)活性的影响。年轻人和老年人的HK活动差异中，年龄分别占51%和23%。家族性AD和散发性AD的病程分别占HK水平的32%和38%。己糖激酶活性随着年龄的增长而增加，并不能区分家族性和散发性AD。

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Leukocyte hexokinase activity in aging and Alzheimer disease.

We determined the effects of clinical variables on hexokinase (HK) activity in leukocytes from Alzheimer's disease (AD) patients and controls. Age accounted for 51% of the variance in HK activity in the young and 23% in the old. Duration of illness in both familial and sporadic AD accounted for HK levels by 32 and 38%, respectively. Hexokinase activity increases with age and does not discriminate between familial and sporadic AD.

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来源期刊

Dementia (Basel, Switzerland)

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