{"title":"互补肽及其抗体在t细胞介导的自身免疫性疾病中的应用:髓鞘碱性蛋白实验","authors":"Zhou Shan-Ren, Whitaker John N.","doi":"10.1006/immu.1994.1048","DOIUrl":null,"url":null,"abstract":"<div><p>In this article we review the field of idiotype (Id) network and experimental allergic encephalomyelitis, focusing on the generation of monoclonal antibody anti-Id by using complementary peptide and the investigation of anti-Id immunoregulatory effects on immune responses of B and T cells to specific myelin basic protein peptides <em>in vitro</em> and <em>in vivo</em>.</p></div>","PeriodicalId":79341,"journal":{"name":"ImmunoMethods","volume":"5 2","pages":"Pages 136-147"},"PeriodicalIF":0.0000,"publicationDate":"1994-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/immu.1994.1048","citationCount":"8","resultStr":"{\"title\":\"Use of Complementary Peptides and Their Antibodies in T-Cell-Mediated Autoimmune Disease: Experiments with Myelin Basic Protein\",\"authors\":\"Zhou Shan-Ren, Whitaker John N.\",\"doi\":\"10.1006/immu.1994.1048\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In this article we review the field of idiotype (Id) network and experimental allergic encephalomyelitis, focusing on the generation of monoclonal antibody anti-Id by using complementary peptide and the investigation of anti-Id immunoregulatory effects on immune responses of B and T cells to specific myelin basic protein peptides <em>in vitro</em> and <em>in vivo</em>.</p></div>\",\"PeriodicalId\":79341,\"journal\":{\"name\":\"ImmunoMethods\",\"volume\":\"5 2\",\"pages\":\"Pages 136-147\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1994-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1006/immu.1994.1048\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ImmunoMethods\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1058668784710485\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ImmunoMethods","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1058668784710485","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Use of Complementary Peptides and Their Antibodies in T-Cell-Mediated Autoimmune Disease: Experiments with Myelin Basic Protein
In this article we review the field of idiotype (Id) network and experimental allergic encephalomyelitis, focusing on the generation of monoclonal antibody anti-Id by using complementary peptide and the investigation of anti-Id immunoregulatory effects on immune responses of B and T cells to specific myelin basic protein peptides in vitro and in vivo.
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