{"title":"神经递质对人类生长激素分泌的控制。","authors":"E Ghigo, E Arvat, J Bellone, J Ramunni, F Camanni","doi":"10.1515/jpem.1993.6.3-4.263","DOIUrl":null,"url":null,"abstract":"<p><p>Growth hormone secretion is mainly regulated by the interplay of GHRH and somatostatin, two specific hypophysiotrophic neurohormones. In addition to GHRH and somatostatin, many neurotransmitters and neuropeptides influence GH secretion mainly by acting at the hypothalamic level. This paper focuses on the stimulatory role of acetylcholine, arginine and galanin as well as on the inhibitory influence of catecholamines which is mediated by the activation of beta-adrenergic receptors. Attention will be given to the age-related changes in the neural control of GH secretion from childhood to old age.</p>","PeriodicalId":79383,"journal":{"name":"The Journal of pediatric endocrinology","volume":"6 3-4","pages":"263-6"},"PeriodicalIF":0.0000,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/jpem.1993.6.3-4.263","citationCount":"33","resultStr":"{\"title\":\"Neurotransmitter control of growth hormone secretion in humans.\",\"authors\":\"E Ghigo, E Arvat, J Bellone, J Ramunni, F Camanni\",\"doi\":\"10.1515/jpem.1993.6.3-4.263\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Growth hormone secretion is mainly regulated by the interplay of GHRH and somatostatin, two specific hypophysiotrophic neurohormones. In addition to GHRH and somatostatin, many neurotransmitters and neuropeptides influence GH secretion mainly by acting at the hypothalamic level. This paper focuses on the stimulatory role of acetylcholine, arginine and galanin as well as on the inhibitory influence of catecholamines which is mediated by the activation of beta-adrenergic receptors. Attention will be given to the age-related changes in the neural control of GH secretion from childhood to old age.</p>\",\"PeriodicalId\":79383,\"journal\":{\"name\":\"The Journal of pediatric endocrinology\",\"volume\":\"6 3-4\",\"pages\":\"263-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1515/jpem.1993.6.3-4.263\",\"citationCount\":\"33\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of pediatric endocrinology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1515/jpem.1993.6.3-4.263\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of pediatric endocrinology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/jpem.1993.6.3-4.263","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Neurotransmitter control of growth hormone secretion in humans.
Growth hormone secretion is mainly regulated by the interplay of GHRH and somatostatin, two specific hypophysiotrophic neurohormones. In addition to GHRH and somatostatin, many neurotransmitters and neuropeptides influence GH secretion mainly by acting at the hypothalamic level. This paper focuses on the stimulatory role of acetylcholine, arginine and galanin as well as on the inhibitory influence of catecholamines which is mediated by the activation of beta-adrenergic receptors. Attention will be given to the age-related changes in the neural control of GH secretion from childhood to old age.
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