P Quirk, P Owens, K Moyse, S Chin, C Wall, J Ballard, R Shepherd
{"title":"慢性肝病生长迟缓儿童血浆中胰岛素样生长因子I和II降低。","authors":"P Quirk, P Owens, K Moyse, S Chin, C Wall, J Ballard, R Shepherd","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>This study shows that blood from young children (< 3 years) with end stage liver disease, contains less IGF-I, IGF-II and IGFBPs than blood from normally growing children without liver disease, despite the provision of adequate calories. These low levels are likely to contribute to growth failure in children with end stage liver disease.</p>","PeriodicalId":77148,"journal":{"name":"Growth regulation","volume":"4 1","pages":"35-8"},"PeriodicalIF":0.0000,"publicationDate":"1994-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Insulin-like growth factors I and II are reduced in plasma from growth retarded children with chronic liver disease.\",\"authors\":\"P Quirk, P Owens, K Moyse, S Chin, C Wall, J Ballard, R Shepherd\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study shows that blood from young children (< 3 years) with end stage liver disease, contains less IGF-I, IGF-II and IGFBPs than blood from normally growing children without liver disease, despite the provision of adequate calories. These low levels are likely to contribute to growth failure in children with end stage liver disease.</p>\",\"PeriodicalId\":77148,\"journal\":{\"name\":\"Growth regulation\",\"volume\":\"4 1\",\"pages\":\"35-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1994-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Growth regulation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Growth regulation","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Insulin-like growth factors I and II are reduced in plasma from growth retarded children with chronic liver disease.
This study shows that blood from young children (< 3 years) with end stage liver disease, contains less IGF-I, IGF-II and IGFBPs than blood from normally growing children without liver disease, despite the provision of adequate calories. These low levels are likely to contribute to growth failure in children with end stage liver disease.