{"title":"[肝脏溶酶体因子的免疫抑制作用(作者译)]。","authors":"H Bockhorn, G E Schrempf-Decker, D P Baron","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>A lysosomal factor isolated from liver tissue (LF) reveals a strong suppressive effect on the in vitro immune response. LF is not species specific and is able to act specifically on the responder function of mitogen or alloantigen-mediated lymphocyte proliferation. The peculiar immunological feature of the liver that it induces a pronounced immunological hyporeactivity can be explained by a similar effect of LF on the cellular immune response in vivo which leads to a reduced rejection of the allotransplanted organ.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"125-8"},"PeriodicalIF":0.0000,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Immunosuppressive effect of lysosomal factors in the liver (author's transl)].\",\"authors\":\"H Bockhorn, G E Schrempf-Decker, D P Baron\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A lysosomal factor isolated from liver tissue (LF) reveals a strong suppressive effect on the in vitro immune response. LF is not species specific and is able to act specifically on the responder function of mitogen or alloantigen-mediated lymphocyte proliferation. The peculiar immunological feature of the liver that it induces a pronounced immunological hyporeactivity can be explained by a similar effect of LF on the cellular immune response in vivo which leads to a reduced rejection of the allotransplanted organ.</p>\",\"PeriodicalId\":75704,\"journal\":{\"name\":\"Chirurgisches Forum fur experimentelle und klinische Forschung\",\"volume\":\" \",\"pages\":\"125-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1980-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chirurgisches Forum fur experimentelle und klinische Forschung\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chirurgisches Forum fur experimentelle und klinische Forschung","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Immunosuppressive effect of lysosomal factors in the liver (author's transl)].
A lysosomal factor isolated from liver tissue (LF) reveals a strong suppressive effect on the in vitro immune response. LF is not species specific and is able to act specifically on the responder function of mitogen or alloantigen-mediated lymphocyte proliferation. The peculiar immunological feature of the liver that it induces a pronounced immunological hyporeactivity can be explained by a similar effect of LF on the cellular immune response in vivo which leads to a reduced rejection of the allotransplanted organ.
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