[应用二月桂酸荧光素诊断囊性纤维化患者胰腺功能不全[作者简介]。

Monatsschrift fur Kinderheilkunde Pub Date : 1980-04-01
W Schönberger, D Weitzel
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引用次数: 0

摘要

用二光酸荧光素进行无管胰功能试验是首次在儿童中进行,该试验是基于胰腺特异性芳基酯酶对试验物质的皂化作用,并已在成人中得到证实。在减少试验剂量和饮液量后,进行试验没有任何困难。囊性纤维化患者从二月桂酸荧光素释放并经肾脏排泄的荧光素的消除明显少于正常受试者。因此,在其修改形式的儿童测试可以提供足够的区分正常和病理胰腺功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Diagnosis of pancreatic insufficiency with fluorescein dilaurate in patients with cystic fibrosis (author's transl)].

The tubeless pancreas-function test with fluorescein dilaurate, which is based on the saponification of the test substance by pancreas-specific arylesterases, and which has proved itself in adults, was given to children for the first time. After reduction of the size of the test dose and the amount of liquid to be drunk, there were no difficulties in carrying out the test. Elimination of the fluorescein released from the flourescein dilaurate and excreted via the kidneys was clearly less in patients with cystic fibrosis than in normal subjects. Thus, the test in its modified form for children can provide adequate differentiation between normal and pathological pancreas function.

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