V I Shamaev, T V Krutova, R F D'yachkovskaya, D B Korman, O S Shkrob, N A Kuznetsov
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The effect of diazane on the proliferation of human tumor cells.
The effect of the antitumorigenic agent diazane (1,2-bis-diazoacetylethane) in the cells of 30 human tumors cultured in vivo in diffusion chambers, implanted intraperitoneally into mice. Twenty-four hours after the introduction of diazane, a decrease in the proportion of DNA-synthesizing cells and the intensity of DNA synthesis to 30--50% of the control values is observed. By 48 hours, the values of these parameters had returned to the initial level.
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