[肺挫伤的实验动物研究]。

R Fricke, M Bartel
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引用次数: 0

摘要

采用大鼠动物实验方法对肺挫伤进行分离。创伤的机制是用钢瓶在胸壁上反弹。肉眼可见的肺改变、肺重量、继发损伤的频率以及死亡率是病变的参数。肺部改变显示人类肺挫伤社区。该模型适用于肺挫伤的组织学和形态学改变的描述,以及肺挫伤的发病机制和诊断参数的探索。肺挫伤的强度受到最初血管破裂的限制。为了临床治疗的检验和有限肺挫伤的释放,需要具有其他创伤机制的模型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Experimental animal studies on lung contusion].

Isolating lung contusions were represented by means of animal experiments in rats. The mechanism of the trauma was a bounce against the thorax wall with a steel cylinder. Macroscopic pulmonary alterations, lung weights, the frequency of secondary injuries as well as the mortality rate are the parameters of the lesion. The lung alterations shows communities with human lung contusions. The model is suitable for the specification of histological and morphological alterations and for the pathogenesis of lung contusions as well as for the quest of diagnostic parameters. The intensity of the lung contusion is limited by initial rupture of vessels. To the test of clinical therapy and for the release of limited lung contusions there are required models with other mechanisms of trauma.

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