{"title":"多巴胺能参与注意力:一种新的动物模型","authors":"R.J Katz, K Schmaltz","doi":"10.1016/0364-7722(81)90099-0","DOIUrl":null,"url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. Adult male outbred albino mice were acutely injected with either of two dopamine (DA) agonists; Apomorphine, a receptor agonist, or Amantadine, a DA releasing agent.</p></span></li><li><span>2.</span><span><p>2. Both drugs produced dose-related alterations in initial Y-maze behavior, consisting of significantly increased proportions of 2-arm entries.</p></span></li><li><span>3.</span><span><p>3. This behavior has previously been shown to reflect an abnormal attentional process.</p></span></li><li><span>4.</span><span><p>4. Thus DA activation may cause sensory perseveration.</p></span></li><li><span>5.</span><span><p>5. The implications of this finding for DA theories of psychopathology is discussed.</p></span></li></ul></div>","PeriodicalId":20801,"journal":{"name":"Progress in neuro-psychopharmacology","volume":"4 6","pages":"Pages 585-590"},"PeriodicalIF":0.0000,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0364-7722(81)90099-0","citationCount":"51","resultStr":"{\"title\":\"Dopaminergic involvement in attention a novel animal model\",\"authors\":\"R.J Katz, K Schmaltz\",\"doi\":\"10.1016/0364-7722(81)90099-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p></p><ul><li><span>1.</span><span><p>1. Adult male outbred albino mice were acutely injected with either of two dopamine (DA) agonists; Apomorphine, a receptor agonist, or Amantadine, a DA releasing agent.</p></span></li><li><span>2.</span><span><p>2. Both drugs produced dose-related alterations in initial Y-maze behavior, consisting of significantly increased proportions of 2-arm entries.</p></span></li><li><span>3.</span><span><p>3. This behavior has previously been shown to reflect an abnormal attentional process.</p></span></li><li><span>4.</span><span><p>4. Thus DA activation may cause sensory perseveration.</p></span></li><li><span>5.</span><span><p>5. The implications of this finding for DA theories of psychopathology is discussed.</p></span></li></ul></div>\",\"PeriodicalId\":20801,\"journal\":{\"name\":\"Progress in neuro-psychopharmacology\",\"volume\":\"4 6\",\"pages\":\"Pages 585-590\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1981-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0364-7722(81)90099-0\",\"citationCount\":\"51\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Progress in neuro-psychopharmacology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0364772281900990\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Progress in neuro-psychopharmacology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0364772281900990","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Dopaminergic involvement in attention a novel animal model
1.
1. Adult male outbred albino mice were acutely injected with either of two dopamine (DA) agonists; Apomorphine, a receptor agonist, or Amantadine, a DA releasing agent.
2.
2. Both drugs produced dose-related alterations in initial Y-maze behavior, consisting of significantly increased proportions of 2-arm entries.
3.
3. This behavior has previously been shown to reflect an abnormal attentional process.
4.
4. Thus DA activation may cause sensory perseveration.
5.
5. The implications of this finding for DA theories of psychopathology is discussed.
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