{"title":"放射性解毒内毒素预处理白细胞的促凝活性。","authors":"T Szilágyi, H Csernyánszky, E Gazdy, L Bertók","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Rabbits were treated with Escherichia coli 089 endotoxin detoxified by ionizing irradiation (60 Co-gamma). The leukocytes (PMNs in 90%) obtained from rabbits that had been treated with the mother endotoxin elicited a well defined, those obtained from rabbits pretreated with detoxified endotoxin elicited a less pronounced, procoagulant activity. It is suggested that the procoagulant effect may play a part in the mechanism of the local Shwartzman phenomenon.</p>","PeriodicalId":75387,"journal":{"name":"Acta microbiologica Academiae Scientiarum Hungaricae","volume":"27 3","pages":"191-4"},"PeriodicalIF":0.0000,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The procoagulant activity of leukocytes pretreated with radiodetoxified endotoxin.\",\"authors\":\"T Szilágyi, H Csernyánszky, E Gazdy, L Bertók\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Rabbits were treated with Escherichia coli 089 endotoxin detoxified by ionizing irradiation (60 Co-gamma). The leukocytes (PMNs in 90%) obtained from rabbits that had been treated with the mother endotoxin elicited a well defined, those obtained from rabbits pretreated with detoxified endotoxin elicited a less pronounced, procoagulant activity. It is suggested that the procoagulant effect may play a part in the mechanism of the local Shwartzman phenomenon.</p>\",\"PeriodicalId\":75387,\"journal\":{\"name\":\"Acta microbiologica Academiae Scientiarum Hungaricae\",\"volume\":\"27 3\",\"pages\":\"191-4\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1980-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta microbiologica Academiae Scientiarum Hungaricae\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta microbiologica Academiae Scientiarum Hungaricae","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
用电离辐射解毒大肠杆菌089内毒素(60 co - γ)治疗家兔。用母体内毒素处理的兔的白细胞(pmn占90%)引起了一个明确的定义，用解毒内毒素预处理的兔的白细胞引起了一个不太明显的促凝活性。提示促凝剂作用可能参与局部史瓦兹曼现象的发生机制。
The procoagulant activity of leukocytes pretreated with radiodetoxified endotoxin.
Rabbits were treated with Escherichia coli 089 endotoxin detoxified by ionizing irradiation (60 Co-gamma). The leukocytes (PMNs in 90%) obtained from rabbits that had been treated with the mother endotoxin elicited a well defined, those obtained from rabbits pretreated with detoxified endotoxin elicited a less pronounced, procoagulant activity. It is suggested that the procoagulant effect may play a part in the mechanism of the local Shwartzman phenomenon.
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