J Wembacher, I Senftleber, J Gokel, C Hammer, W Brendel
{"title":"[自然和人工同种异体移植物淋巴细胞的评估(作者译)]。","authors":"J Wembacher, I Senftleber, J Gokel, C Hammer, W Brendel","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Transfer of \"passenger lymphocytes\" within a transplant initiates allogeneic rejection. As compared with peripheral lymphocytes, which show no different in vitro reaction, infiltrating cells from natural and artificial grafts are good stimulator, bad responder but powerful suppressor cells. These T-suppressor cells, which arose during rejection are enriched in the graft. The assumption is that the function of this relatively small number of lymphocytes is to suppress the local immunological rejection mechanisms. They cannot inhibit the proliferation of peripheral cytotoxic cells.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"115-9"},"PeriodicalIF":0.0000,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Assessment of lymphatic cells in natural and artificial allografts (author's transl)].\",\"authors\":\"J Wembacher, I Senftleber, J Gokel, C Hammer, W Brendel\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Transfer of \\\"passenger lymphocytes\\\" within a transplant initiates allogeneic rejection. As compared with peripheral lymphocytes, which show no different in vitro reaction, infiltrating cells from natural and artificial grafts are good stimulator, bad responder but powerful suppressor cells. These T-suppressor cells, which arose during rejection are enriched in the graft. The assumption is that the function of this relatively small number of lymphocytes is to suppress the local immunological rejection mechanisms. They cannot inhibit the proliferation of peripheral cytotoxic cells.</p>\",\"PeriodicalId\":75704,\"journal\":{\"name\":\"Chirurgisches Forum fur experimentelle und klinische Forschung\",\"volume\":\" \",\"pages\":\"115-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1980-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chirurgisches Forum fur experimentelle und klinische Forschung\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chirurgisches Forum fur experimentelle und klinische Forschung","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Assessment of lymphatic cells in natural and artificial allografts (author's transl)].
Transfer of "passenger lymphocytes" within a transplant initiates allogeneic rejection. As compared with peripheral lymphocytes, which show no different in vitro reaction, infiltrating cells from natural and artificial grafts are good stimulator, bad responder but powerful suppressor cells. These T-suppressor cells, which arose during rejection are enriched in the graft. The assumption is that the function of this relatively small number of lymphocytes is to suppress the local immunological rejection mechanisms. They cannot inhibit the proliferation of peripheral cytotoxic cells.