氯化钙对氯乙醇和甘油引起的猫总体行为改变的影响。

D B Beleslin, R Samardzic, S K Krstić, M Strbac
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引用次数: 0

摘要

研究了将氯化钙注射到群居未麻醉猫的脑室中,对猫的发声(愤怒、嘶嘶和咆哮)、打斗(爪爪攻击、爪爪防御和咬人)、抽丝病、震颤和由同样注射的卡巴酚和埃瑟林引起的阵挛性惊厥的影响。氯化钙抑制或几乎完全消除了由乙醇和甘油引起的发声和战斗。另一方面,氯化钙对氯乙醇和甘油引起的泪腺、震颤和阵挛性惊厥无显著影响。很明显,氯化钙可以将发声和战斗从自主和运动现象中“分离”出来,如由乙醇和甘油引起的抽丝、震颤和阵挛性抽搐。氯化钙很可能是通过对毒蕈碱中枢胆碱感受部位的非特异性稳定作用抑制了碳乙醇和eserine产生的发声和战斗。这些结果进一步支持了过量钙离子在中枢神经系统中也具有阿托品样作用的观点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of calcium chloride on gross behavioural changes produced by carbachol and eserine in cats.

The effect of calcium chloride injected into the cerebral ventricles of group-housed unanaesthetized cats upon vocalization (rage, hissing and snarling), fighting (attack with paws and claws, defense with paws and claws and biting), mydriasis, tremor and clonic-tonic convulsions produced by carbachol and eserine injected similarly was investigated. Calcium chloride depressed or almost completely abolished the vocalization and fighting due to carbachol and eserine. On the other hand, mydriasis, tremor and clonic-tonic convulsions evoked by carbachol and eserine were not significantly changed by calcium chloride. It is apparent that calcium chloride can "dissociate" vocalization and fighting from autonomic and motor phenomena such as mydriasis, tremor and clonic-tonic convulsions caused by carbachol and eserine. Calcium chloride inhibited the vocalization and fighting produced by carbachol and eserine most probably by a nonspecific stabilizing action on central muscarinic cholinoceptive sites. These results further support the view that calcium ions in excess have an atropine-like action also in the central nervous system.

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