[与母体免疫球蛋白存在有关的母亲和新生儿明显的短暂性高甲状腺素血症]。

Comptes rendus des seances de l'Academie des sciences. Serie D, Sciences naturelles Pub Date : 1980-12-15

J L Vandalem, P Czernichow, G Henmen

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引用次数: 0

摘要

一些新生儿(筛查先天性hypothyroïdism)和他们的母亲被发现表现出明显的孤立性高甲状腺蛋白血症。发现一种大分子物质(150000道尔顿)具有明显的免疫反应性，其特征为免疫球蛋白，能够结合TSH和兔IgG。这些母体免疫球蛋白被被动地转移到新生儿体内，并干扰各种放射免疫测定。

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[Apparent transitory hyperthyrotropinemia of mothers and newborn infants related to the presence of maternal immunoglobulins].

Some newborns infants (screened for congenital hypothyroïdism) and their mothers were found to present an apparent isolated hyperthyrotropinemia. A large molecular size material (150 000 dalton) was found to carry the apparent immunoreactivity and was characterized as immunoglobulins, capable of binding TSH as well as Rabbit IgG. These maternal immunoglobulins are passively transferred to the newborn infants and interfere in various radioimmunoassays.

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Comptes rendus des seances de l'Academie des sciences. Serie D, Sciences naturelles

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