[非洲伯基特淋巴瘤连续细胞系t(2;8)和t(8;22)易位]。

Comptes rendus des seances de l'Academie des sciences. Serie D, Sciences naturelles Pub Date : 1980-09-15

A Bernheim, R Berger, G Lenoir

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引用次数: 0

摘要

染色体研究用EBV阳性的非洲伯基特淋巴瘤细胞系进行。变异易位4例，2例为t(2;8) (p12;q23 ~ 24)， 2例为t(8;22) (q23 ~ 24;q11)。在EBV阳性或阴性的非非洲淋巴瘤或伯基特型白血病中观察到相同的易位。这些结果显示了伯基特淋巴瘤白血病的独特性，并强调了8号染色体重排在这种肿瘤中的重要性。

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[Translocations t(2;8) and t(8;22) in continuous cell lines of African Burkitt's lymphoma].

Chromosome studies were performed by EBV positive African Burkitt lymphoma cell lines. Variant translocations were found in 4 cases: two with t(2;8) (p12;q23 ou 24) and two with t(8;22) (q23 or 24;q11). Identical translocations were observed in EBV positive or negative non-african lymphomas or Burkitt type leukemia. These results show the uniqueness of Burkitt lymphoma leukemia and stress the importance of chromosome 8 rearrangement in this tumor.

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Comptes rendus des seances de l'Academie des sciences. Serie D, Sciences naturelles

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