{"title":"随机化试验应用于流式细胞术直方图","authors":"Reinhold C Mann, Russell E Hand Jr","doi":"10.1016/0010-468X(83)90029-6","DOIUrl":null,"url":null,"abstract":"<div><p>The randomization test is used to test the hypothesis that two groups of flow cytometric histograms consist of samples from the same probability density function. The hypothesis is tested channel-by-channel. This non-parametric method does not require any assumptions as to the probability density functions involved and is therefore applicable to histograms from many different biological systems. Moreover, it allows for very few histograms per group so that the hypothesis can be tested on the basis of a small number of experiments. The procedure is implemented in PASCAL on a mini computer which is connected to a flow cytometer.</p></div>","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"17 1","pages":"Pages 95-100"},"PeriodicalIF":0.0000,"publicationDate":"1983-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(83)90029-6","citationCount":"2","resultStr":"{\"title\":\"The randomization test applied to flow cytometric histograms\",\"authors\":\"Reinhold C Mann, Russell E Hand Jr\",\"doi\":\"10.1016/0010-468X(83)90029-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The randomization test is used to test the hypothesis that two groups of flow cytometric histograms consist of samples from the same probability density function. The hypothesis is tested channel-by-channel. This non-parametric method does not require any assumptions as to the probability density functions involved and is therefore applicable to histograms from many different biological systems. Moreover, it allows for very few histograms per group so that the hypothesis can be tested on the basis of a small number of experiments. The procedure is implemented in PASCAL on a mini computer which is connected to a flow cytometer.</p></div>\",\"PeriodicalId\":75731,\"journal\":{\"name\":\"Computer programs in biomedicine\",\"volume\":\"17 1\",\"pages\":\"Pages 95-100\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1983-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0010-468X(83)90029-6\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Computer programs in biomedicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0010468X83900296\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computer programs in biomedicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0010468X83900296","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The randomization test applied to flow cytometric histograms
The randomization test is used to test the hypothesis that two groups of flow cytometric histograms consist of samples from the same probability density function. The hypothesis is tested channel-by-channel. This non-parametric method does not require any assumptions as to the probability density functions involved and is therefore applicable to histograms from many different biological systems. Moreover, it allows for very few histograms per group so that the hypothesis can be tested on the basis of a small number of experiments. The procedure is implemented in PASCAL on a mini computer which is connected to a flow cytometer.