随机化试验应用于流式细胞术直方图

Reinhold C Mann, Russell E Hand Jr
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引用次数: 2

摘要

随机化检验用于检验两组流式细胞术直方图由来自相同概率密度函数的样本组成的假设。这一假设经过了逐个频道的检验。这种非参数方法不需要对所涉及的概率密度函数进行任何假设,因此适用于许多不同生物系统的直方图。此外,它允许每组很少的直方图,因此假设可以在少量实验的基础上进行检验。该程序在连接流式细胞仪的微型计算机上用PASCAL语言实现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The randomization test applied to flow cytometric histograms

The randomization test is used to test the hypothesis that two groups of flow cytometric histograms consist of samples from the same probability density function. The hypothesis is tested channel-by-channel. This non-parametric method does not require any assumptions as to the probability density functions involved and is therefore applicable to histograms from many different biological systems. Moreover, it allows for very few histograms per group so that the hypothesis can be tested on the basis of a small number of experiments. The procedure is implemented in PASCAL on a mini computer which is connected to a flow cytometer.

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