方法:研究血液在凝血过程中的流变特性。

Biorheology. Supplement : the official journal of the International Society of Biorheology Pub Date : 1984-01-01 DOI:10.3233/bir-1984-23s103

E Fukada, Y Sugiura, M Date, M Kaibara

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引用次数: 11

摘要

综述了纤维蛋白原溶液、血浆和血液凝血的体外流变学研究。开发了多个粘弹性记录仪(MVER)和粘弹性记录仪(VER)，用于测定凝血过程中的动态刚性模量(G’)和损失模量(G”)。讨论了一些参数对凝血和纤维蛋白凝块性质的影响。测量参数包括测量频率、测量剪切应变和测量单元表面涂层。比较了正常血浆和格兰兹曼病患者血浆凝血过程中动态刚性的变化。通过检测高次谐波频率下的应力，确定了G'和G"的非线性项。

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Methods to study rheological properties of blood during clotting.

In vitro rheological studies on clotting of fibrinogen solution, plasma and blood are reviewed. Multiple viscoelastorecorder (MVER) and viscoelastorecorder (VER) were developed for determining the dynamic rigidity modulus (G') and loss modulus (G") during clotting. The effect of some parameters on clotting and the properties of fibrin clot are discussed. The parameters include measuring frequency, measuring shear strain and surface coating of measuring cell. The change of dynamic rigidity during clotting was compared between normal plasma and plasma from patient with Glanzmann's disease. By detecting the stress at the higher harmonic frequency, the non-linear terms of G' and G" were determined.

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Biorheology. Supplement : the official journal of the International Society of Biorheology

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