[对血清中凝集素的血清学反应较弱的A型和O型血]。

Bilten za hematologiju i transfuziju Pub Date : 1984-01-01
S Simić
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引用次数: 0

摘要

在正常情况下,抗a和抗b凝集素很少弱,很少完全不存在。凝集反应取决于温度。用酶(木瓜蛋白酶)处理红细胞会加强这种作用,并且还取决于所调查的人的基因型。在抗b凝集素中更常观察到改变。2例有缺陷的A和O型血,在常规调查中缺乏抗b凝集素。用木瓜蛋白酶处理4℃的红细胞表明存在抗b凝集素,其血清学表达较弱。用激光比浊法测定吸附和洗脱前后的免疫球蛋白浓度,也表明该凝集素的存在。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Blood groups A and O with a weaker serological reactivity to agglutinins in the serum].

In normal conditions anti-A and anti-B agglutinins are seldom weak and very seldom they are completely absent. Agglutination reaction depends on temperature. It is intensified by treatment of erythrocytes with enzymes (papain) and is also dependent on genotype of the person investigated. Alterations are more frequently observed in anti-B agglutinin. Two cases with defective A and O blood groups are presented, with anti-B agglutinin missing at routine investigation. Treatment of erythrocytes at 4 degrees C with papain indicated the presence of anti-B agglutinin which has a weaker serological expression. Assessment of immunoglobulin concentration by laser nephelometry before and after adsorption and elution, also indicated the presence of this agglutinin.

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